A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, HPLC of Formula: C9H15NO2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. HPLC of Formula: C9H15NO2, Name is Quinuclidin-3-yl acetate, molecular formula is C9H15NO2. In a Article, authors is Primozie, Ines£¬once mentioned of HPLC of Formula: C9H15NO2
Influence of the acyl moiety on the hydrolysis of quinuclidinium esters catalyzed by butyrylcholinesterase
Eight chiral esters of quinuclidin-3-ol and butyric, acetic, pivalic and benzoic acid were synthesized as well as their racemic and chiral, quaternary N-benzyl derivatives. All racemic and chiral quaternary compounds were studied as substrates and/or inhibitors of horse serum butyrylcholinesterase (BChE). The best substrate for the enzyme was (R)-N-benzyl butyrate. The rates of hydrolysis decreased in order (R)-butyrate (R)-acetate (7-fold slower) < (R)-pivalate (8-fold slower) < (R)-benzoate (9-fold slower reaction), while (S)-N-benzyl esters were much poorer substrates (320 (butyrate)-4360-fold slower (pivalate) than the appropriate (R)-enantiomer). For all (S)-N-benzyl esters excluding (S)-N-benzyl acetate inhibition constants were determined (Ka = 3.3.60 mumol dm-3). The hydrolysis of racemic mixtures of N-benzyl esters proceeded 1.4 (for acetate)-5.1 (for benzoate) times slower than that of pure (R)-enantiomers of the corresponding concentrations due to the inhibition with (S)-enantiomers. Change of the acyl moiety of the substrate effected both activity and stereoselectivity of the BChE.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about HPLC of Formula: C9H15NO2
Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H78N | ChemSpider