The important role of 827-61-2

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Chemistry is traditionally divided into organic and inorganic chemistry. category: quinuclidine, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 827-61-2

Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018)

A practical diastereoselective synthetic method for 8018 enantiopure isomers is described. The intramolecular asymmetric epoxidation of mono-sulfonate 4 was applied for the execution of the synthesis of the key chiral building block for the first time. The isomers were obtained with 70-76% yields in 99-100% ee.

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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H60N | ChemSpider