Discovery of APR-246

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5291-32-7 is helpful to your research. HPLC of Formula: C10H17NO3

5291-32-7, Name is APR-246, belongs to quinuclidine compound, is a common compound. HPLC of Formula: C10H17NO3In an article, once mentioned the new application about 5291-32-7.

NEW STRATEGIES FOR TREATING MELANOMA

The present invention relates to a p53-activating agent capable of transferring wild-type tumor protein p53 (p53) from an inactive conformation into an active conformation capable of inducing apoptosis, for use in the treatment of melanoma, wherein said p53-activating agent is administered simultaneously or sequentially with a BRAF-inhibiting agent capable of inhibiting activity of serine/threonine-protein kinase B-Raf (BRAF) comprising an activating mutation.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5291-32-7 is helpful to your research. HPLC of Formula: C10H17NO3

Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H166N | ChemSpider