Synthetic Route of 5291-32-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.5291-32-7, Name is APR-246, molecular formula is C10H17NO3. In a article£¬once mentioned of 5291-32-7
METHODS FOR MODULATING CHEMOTHERAPEUTIC CYTOTOXICITY
Disclosed herein are methods of reducing cytotoxicity of a chemotherapeutic agent to non-cancer cells by administering to a subject with cancer an effective amount of an agent that inhibits CD47 signaling and a chemotherapeutic agent. Example disclosed methods reduce cardiotoxicity of a chemotherapeutic agent. Also disclosed are methods of increasing cytotoxicity of a chemotherapeutic agent in cancer cells by administering to a subject with a tumor an effective amount of an agent that inhibits CD47 signaling and a chemotherapeutic agent. In some embodiments, the inhibitor of CD47 signaling is administered to the subject before, during, or after the administration of the chemotherapeutic agent.
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Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H167N | ChemSpider