In an article, author is HACKSELL, U, once mentioned the application of 272778-12-8, Name is (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one, molecular formula is C39H46F2N2O5Si2, molecular weight is 716.96, MDL number is MFCD08460200, category is quinuclidines. Now introduce a scientific discovery about this category, SDS of cas: 272778-12-8.
QUINUCLIDIN-2-ENE – BASED MUSCARINIC ANTAGONISTS
A series of achiral 3-heteroaryl substituted quinuclidin-2-ene derivatives and related compounds have been synthesized by facile methods. The compounds were evaluated for muscarinic and antimuscarinic properties in receptor binding studies using (-)-[H-3]-QNB as the radioligand and ina functional assay using isolated guinea pig urinary bladder. 3-(2-Benzofuranyl)-quinuclidin-2-ene (15) displayed the highest M(1)-receptor affinity in the present series (K-i = 9.6 nM).
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Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider