Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 112-62-9, Name is Methyl oleate, SMILES is CCCCCCCC/C=CCCCCCCCC(OC)=O, belongs to quinuclidines compound. In a document, author is McDonald, Ivar M., introduce the new discover, SDS of cas: 112-62-9.
Discovery of a novel series of quinolone alpha 7 nicotinic acetylcholine receptor agonists
High throughput screening led to the identification of a novel series of quinolone alpha 7 nicotinic acetylcholine receptor (nAChR) agonists. Optimization of an HTS hit (1) led to 4-phenyl-1-(quinuclidin-3-ylmethyl)quinolin-2(1H)-one, which was found to be potent and selective. Poor brain penetrance in this series was attributed to transporter-mediated efflux, which was in turn due to high pK(a). A novel 4-fluoroquinuclidine significantly lowered the pK(a) of the quinuclidine moiety, reducing efflux as measured by a Caco-2 assay. (C) 2013 Elsevier Ltd. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 112-62-9 is helpful to your research. SDS of cas: 112-62-9.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider