Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner.In an article, author is Primozic, Ines, once mentioned the application of 2179-57-9, Name is Diallyldisulfide, molecular formula is C6H10S2, molecular weight is 146.2736, MDL number is MFCD00008656, category is quinuclidine. Now introduce a scientific discovery about this category, Recommanded Product: Diallyldisulfide.
Binding Modes of Quinuclidinium Esters to Butyrylcholinesterase
The orientations of chiral quinuclidin-3-ol esters and benzoylcholine in the active site of horse butyrylcholinesterase have been investigated by flexible ligand docking. Change of the esters’ acyl moiety as well as the substituent at the quinuclidinium nitrogen atom affected the activity and stereoselectivity of the biotransformations. Analysis of interactions in the active site revealed the most important binding patterns for enantiomers, which define their reactivity. Calculated Gibbs energies of binding obtained by molecular docking simulations were well correlated to the experimentally determined binding affinities of the investigated chiral esters. (doi: 10.5562/cca2060)
Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.Interested yet? Keep reading other articles of 2179-57-9, you can contact me at any time and look forward to more communication. Recommanded Product: Diallyldisulfide.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider