Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner.In an article, author is Brown, GR, once mentioned the application of 79-39-0, Name is Methacrylamide, molecular formula is C4H7NO, molecular weight is 85.1045, MDL number is MFCD00008018, category is quinuclidine. Now introduce a scientific discovery about this category, Recommanded Product: 79-39-0.
Novel optimised quinuclidine squalene synthase inhibitors
Optimised quinuclidine squalene synthase (SQS) inhibitors are reported; 3-[2-(2-allyl-4-(2-ethoxy carbonylethyl)phenyl)ethynyl]quinuclidin-3-ol 1c, is a potent inhibitor of rat (KI = 6 nM) and human (KI = 43 nM) microsomal SQS; the oral ED(50) of 1c, for the inhibition of rat cholesterol biosynthesis was 1.3+/-0.45 mg/kg and for the R-enantiomer 1m, 0.8+/-0.2 mg/kg, with the corresponding R-carboxylic acid 6a, being 0.9+/-0.25 mg/kg. (C) 1997 Elsevier Science Ltd. All rights reserved.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.Interested yet? Keep reading other articles of 79-39-0, you can contact me at any time and look forward to more communication. Recommanded Product: 79-39-0.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider