Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis,preparation and modification of special coatings, and research on the structure and performance of functional materials. 25265-77-4, Name is 2,2,4-Trimethyl-1,3-pentanediol 1-monoisobutyrate, SMILES is CC(C(C(C)(COC(C(C)C)=O)C)O)C.CC(C)C(OC(C(C)C)C(C)(C)CO)=O, belongs to quinuclidine compound. In a document, author is Brown, GR, introduce the new discover, HPLC of Formula: https://www.ambeed.com/products/25265-77-4.html.
Optimised quinuclidine squalene synthase (SQS) inhibitors are reported; 3-[2-(2-allyl-4-(2-ethoxy carbonylethyl)phenyl)ethynyl]quinuclidin-3-ol 1c, is a potent inhibitor of rat (KI = 6 nM) and human (KI = 43 nM) microsomal SQS; the oral ED(50) of 1c, for the inhibition of rat cholesterol biosynthesis was 1.3+/-0.45 mg/kg and for the R-enantiomer 1m, 0.8+/-0.2 mg/kg, with the corresponding R-carboxylic acid 6a, being 0.9+/-0.25 mg/kg. (C) 1997 Elsevier Science Ltd. All rights reserved.
Because enzymes can increase reaction rates by enormous factors, typically producing only a single product in quantitative yield, they are the focus of active research.In my other articles, you can also check out more blogs about 25265-77-4. HPLC of Formula: https://www.ambeed.com/products/25265-77-4.html.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider