COA of Formula: https://www.ambeed.com/products/1561-92-8.html, New discoveries in chemical research and development in 2021. Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1561-92-8, Name is Sodium 2-methylprop-2-ene-1-sulfonate, SMILES is C=C(C)CS(=O)([O-])=O.[Na+], belongs to quinuclidine compound. In a article, author is Karolyi, Benedek Imre, introduce new discover of the category.
A series of novel functionalized mono-, bis-and tris-(S)-{[(2S,4R,8R)-8-ethyl-quinuclidin-2-yl](6-methoxyquinolin-4-yl)}methanamines including ferrocene-containing derivatives was obtained by the reaction of the precursor amine with a variety of acylation agents. Their in vitro antitumor activity was investigated against human leukemia (HL-60), human neuroblastoma (SH-SY5Y), human hepatoma (HepG2) and human breast cancer (MCF-7) cells by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)-assay and the 50% inhibitory concentration (IC50) values were determined. Our data indicate that the precursor amine has no antitumor activity in vitro, but the bis-methanamines with ureido-, thioureido and amide-type linkers display attractive in vitro cytotoxicity and cytostatic effects on HL-60, HepG2, MCF-7 and SH-SY5Y cells. Besides H-1- and C-13-NMR methods the structures of the new model compounds were also studied by DFT calculations.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.If you’re interested in learning more about 1561-92-8. The above is the message from the blog manager. COA of Formula: https://www.ambeed.com/products/1561-92-8.html.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider