HPLC of Formula: https://www.ambeed.com/products/1889-67-4.html, New discoveries in chemical research and development in 2021. Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1889-67-4, Name is (2,3-Dimethylbutane-2,3-diyl)dibenzene, SMILES is CC(C)(C1=CC=CC=C1)C(C)(C2=CC=CC=C2)C, belongs to quinuclidine compound. In a article, author is Primozic, Ines, introduce new discover of the category.
The orientations of chiral quinuclidin-3-ol esters and benzoylcholine in the active site of horse butyrylcholinesterase have been investigated by flexible ligand docking. Change of the esters’ acyl moiety as well as the substituent at the quinuclidinium nitrogen atom affected the activity and stereoselectivity of the biotransformations. Analysis of interactions in the active site revealed the most important binding patterns for enantiomers, which define their reactivity. Calculated Gibbs energies of binding obtained by molecular docking simulations were well correlated to the experimentally determined binding affinities of the investigated chiral esters. (doi: 10.5562/cca2060)
Because enzymes can increase reaction rates by enormous factors, typically producing only a single product in quantitative yield, they are the focus of active research.In my other articles, you can also check out more blogs about 1889-67-4. HPLC of Formula: https://www.ambeed.com/products/1889-67-4.html.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider