The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bis(norbornadiene)rhodium (I) tetrafluoroborate( cas:36620-11-8 ) is researched.HPLC of Formula: 36620-11-8.Liu, Gang; Yin, Congcong; Yang, Xuanliang; Li, Anqi; Wang, Minyan; Zhang, Xumu; Dong, Xiu-Qin published the article 《Highly chemo- and enantioselective Rh-catalyzed hydrogenation of β-sulfonyl-α,β-unsaturated ketones: Access to chiral γ-ketosulfones》 about this compound( cas:36620-11-8 ) in Organic Letters. Keywords: chiral gamma ketosulfone preparation sulfonyl unsaturated Ketone enantioselective hydrogenation. Let’s learn more about this compound (cas:36620-11-8).
Rh-catalyzed highly chemo- and enantioselective hydrogenation of β-sulfonyl-α,β-unsaturated ketones was first successfully developed. Remarkably, a variety of enantioenriched γ-ketosulfones were generated in good to high yields with excellent chemo/enantioselectivities (82-99% yields, >99:1 chemoselectivity, 88 to >99% ee). Moreover, the gram-scale asym. hydrogenation was carried out smoothly in 97% yield and 97% ee. Preliminary DFT computations furnished a reasonable explanation for the high chemoselectivity and enantioselectivity.
From this literature《Highly chemo- and enantioselective Rh-catalyzed hydrogenation of β-sulfonyl-α,β-unsaturated ketones: Access to chiral γ-ketosulfones》,we know some information about this compound(36620-11-8)HPLC of Formula: 36620-11-8, but this is not all information, there are many literatures related to this compound(36620-11-8).
Reference:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider