The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bis(norbornadiene)rhodium (I) tetrafluoroborate( cas:36620-11-8 ) is researched.HPLC of Formula: 36620-11-8.Bochat, Andrew J.; Shoba, Veronika M.; Takacs, James M. published the article 《Ligand-Controlled Regiodivergent Enantioselective Rhodium-Catalyzed Alkene Hydroboration》 about this compound( cas:36620-11-8 ) in Angewandte Chemie, International Edition. Keywords: ligand controlled regiodivergent enantioselective rhodium catalyzed alkene hydroboration; chiral alc enantioselective preparation; boronate chiral preparation oxidation; asymmetric catalysis; homogeneous catalysis; hydroboration; regiodivergent reactions; rhodium. Let’s learn more about this compound (cas:36620-11-8).
Regiocontrol in the Rh-catalyzed boration of vinyl arenes is typically dominated by the presence of the conjugated aryl substituent. However, small differences in TADDOL-derived chiral monophosphite ligands can override this effect and direct Rh-catalyzed hydroboration of β-aryl and β-heteroaryl methylidenes by pinacolborane to selectively produce either chiral primary or tertiary borated products. The regiodivergent behavior is coupled with enantiodivergent addition of the borane. The nature of the TADDOL backbone substituents and that of the phosphite moiety function synergistically to direct the sense and extent of regioselectivity and enantioinduction. Twenty substrates undergo each reaction mode with regioselectivity values reaching >20:1 and enantiomer ratios reaching up to 98:2. A variety of subsequent transformations illustrate the potential utility of each product.
There is still a lot of research devoted to this compound(SMILES：[F-][B+3]([F-])([F-])[F-].C12=C3[Rh+]14567(C8=C5C9C6=C7C8C9)C%10=C4C2CC3%10)HPLC of Formula: 36620-11-8, and with the development of science, more effects of this compound(36620-11-8) can be discovered.
Reference:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider