The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (5aS,10bR)-2-(2,4,6-Trichlorophenyl)-4,5a,6,10b-tetrahydro-2H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium tetrafluoroborate( cas:1214711-48-4 ) is researched.Application In Synthesis of (5aS,10bR)-2-(2,4,6-Trichlorophenyl)-4,5a,6,10b-tetrahydro-2H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium tetrafluoroborate.Lin, Qiqiao; Li, Yuanzhen; Das, Deb Kumar; Zhang, Guoxiang; Zhao, Zhifei; Yang, Shuang; Fang, Xinqiang published the article 《N-Heterocyclic carbene-catalyzed desymmetrization of functionalized 1,4-dienes via Stetter Reaction》 about this compound( cas:1214711-48-4 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: desymmetrization diene Stetter reaction heterocyclic carbene catalyst; asym desymmetrization diene heterocyclic carbene catalyst; ketone cyclic enantioselective synthesis; Stetter umpolung reaction asym desymmetrization diene. Let’s learn more about this compound (cas:1214711-48-4).
The asym. desymmetrization of 1,4-dienes via chiral N-heterocyclic carbene catalyzed Stetter-type umpolung reaction was demonstrated. A variety of differently substituted dienes were tolerated very well, affording cyclic ketones with two consecutive stereogenic centers (including one quaternary carbon) in moderate to high yields and with high to excellent enantioselectivities. This work expanded both reaction types of catalytic diene desymmetrizations and substrate diversity in NHC catalyzed desym. transformations.
From this literature《N-Heterocyclic carbene-catalyzed desymmetrization of functionalized 1,4-dienes via Stetter Reaction》,we know some information about this compound(1214711-48-4)Application In Synthesis of (5aS,10bR)-2-(2,4,6-Trichlorophenyl)-4,5a,6,10b-tetrahydro-2H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium tetrafluoroborate, but this is not all information, there are many literatures related to this compound(1214711-48-4).
Reference:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider