The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (5aS,10bR)-2-(2,4,6-Trichlorophenyl)-4,5a,6,10b-tetrahydro-2H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium tetrafluoroborate(SMILESS: ClC1=C(N2N=C3[N+]([C@@]4([H])[C@@](CC5=C4C=CC=C5)([H])OC3)=C2)C(Cl)=CC(Cl)=C1.F[B-](F)(F)F,cas:1214711-48-4) is researched.HPLC of Formula: 36620-11-8. The article 《Carbene-catalyzed activation of cyclopropylcarbaldehydes for Mannich reaction and δ-lactam formation: remote enantioselectivity control and dynamic kinetic asymmetric transformation》 in relation to this compound, is published in Science China: Chemistry. Let’s take a look at the latest research on this compound (cas:1214711-48-4).
An N-heterocyclic carbene (NHC)-catalyzed enantioselective Mannich reaction of the remote γ-carbon of cyclopropylcarbaldehydes was disclosed for the first time to yield δ-lactam compounds such as I [R = C6H5, 2-FC6H4, 2-thienyl, etc.; R1 = Me, Et, 4-O2NBn, R2 = H, Cl, Me, etc.]. Diastereo- and enantiomerically enriched multicyclic δ-lactam compound was afforded as the main product from 8 possible stereo-specific isomers through dynamic kinetic asym. transformation (DYKAT) processes. Multiple chiral functional mols. could be afforded from the lactam products through simple protocols with retentions of the optical purities.
In addition to the literature in the link below, there is a lot of literature about this compound((5aS,10bR)-2-(2,4,6-Trichlorophenyl)-4,5a,6,10b-tetrahydro-2H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-11-ium tetrafluoroborate)COA of Formula: C18H13BCl3F4N3O, illustrating the importance and wide applicability of this compound(1214711-48-4).
Reference:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider