Sun, Ping; Armstrong, Daniel W. published the artcile< Effective enantiomeric separations of racemic primary amines by the isopropyl carbamate-cyclofructan6 chiral stationary phase>, Electric Literature of 120570-05-0, the main research area is primary amine enantioseparation HPLC isopropyl carbamate cyclofructan6 chiral phase; amino acid enantioseparation HPLC isopropyl carbamate cyclofructan6 chiral phase; alc amino enantioseparation HPLC isopropyl carbamate cyclofructan6 chiral phase.
A new chiral stationary phase (CSP) was developed by bonding isopropyl-carbamate functionalized cyclofructan6 (IP-CF6) to the silica gel. It was evaluated by injecting 119 racemic primary amine-containing compounds This CSP showed pronounced enantioselectivity toward all types of primary amines, separating 93% of all tested compounds Baseline separation was achieved even for some simple aliphatic racemic amines that contained no other functionality. The polar organic mode is the effective mobile phase owing to higher efficiency. This new chiral stationary phase showed great potential for preparative-scale separations It is also interesting that the chiral selector, R-naphthylethyl-carbamate functionalized CF6 (RN-CF6), provides complementary selectivity for the relatively few amine analytes that did not sep. on IP-CF6. Thus between the two CSPs, 98% of attempted amine compounds were separated
Journal of Chromatography A published new progress about Amino acid esters Role: ANT (Analyte), ANST (Analytical Study). 120570-05-0 belongs to class quinuclidine, and the molecular formula is C7H14N2, Electric Literature of 120570-05-0.
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider