Clark, R. D.; Muchowski, J. M.; Weinhardt, K. K.; Dillon, M. P.; Lee, C.-H.; Bley, K. R.; Bonhaus, D. W.; Wong, E. H. F.; Eglen, R. M. published the artcile< N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide: a high affinity 5-HT3 receptor partial agonist>, Name: (S)-3-Amino-1-azabicyclo[2.2.2]octane, the main research area is quinuclidinylindolyloxoacetamide enantiomer preparation serotoninergic receptor agonist; serotoninergic receptor partial agonist quinuclidinylindolyloxoacetamide enantiomer.
The enantiomers of the indolyl-2-oxoacetamide I were found to have 5-HT3 receptor partial agonist activity with (R)-I having higher potency than (S)-I.
Bioorganic & Medicinal Chemistry Letters published new progress about 5-HT3 agonists. 120570-05-0 belongs to class quinuclidine, and the molecular formula is C7H14N2, Name: (S)-3-Amino-1-azabicyclo[2.2.2]octane.
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider