Masjedizadeh, Mohammad R.; Parnes, Howard published the artcile< Synthesis of the serotonin ligands, RS-56532-14C and RS-66331-14C from a common labeled intermediate>, Quality Control of 120570-05-0, the main research area is carbon labeled serotonin ligand; RS66331 carbon labeled; RS56532 carbon labeled; naphthalic anhydride intermediate labeled serotonin ligand.
Two approaches towards the synthesis of 3-chloro-4-amino-1,8-naphthalic anhydride-[14C] (I), which served as the common intermediate in the preparation of the two little compounds (II and III, resp.), are described. Although nucleophilic incorporation of the label via KCN was superior to an electrophilic sequence using CO2, the latter approach was adopted since the nitrile could not be hydrolyzed to the desired acid. The specific activities of RS-56532-14C and RS-66331-14C were 56.8 mCi/mmol and 53.7 mCi/mmol, resp.
Journal of Labelled Compounds and Radiopharmaceuticals published new progress about 120570-05-0. 120570-05-0 belongs to class quinuclidine, and the molecular formula is C7H14N2, Quality Control of 120570-05-0.
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider