Akinbobuyi, Babatope published the artcileSynthesis and immunostimulatory activity of substituted TLR7 agonists, Application In Synthesis of 1353016-70-2, the publication is Bioorganic & Medicinal Chemistry Letters (2016), 26(17), 4246-4249, database is CAplus and MEDLINE.
Fifteen new substituted 9-benzyladenines were synthesized as potential TLR7 agonists. These compounds, along with 9 previously reported compounds, were analyzed for TLR7 activity and for the selective stimulation of B cell proliferation. Several functionalized derivatives exhibit significant activity, suggesting their potential for use as vaccine adjuvants.
Bioorganic & Medicinal Chemistry Letters published new progress about 1353016-70-2. 1353016-70-2 belongs to quinuclidine, auxiliary class Other Aromatic Heterocyclic,Carboxylic acid,Amide,Inhibitor,Inhibitor, name is Dbco-acid, and the molecular formula is C19H15NO3, Application In Synthesis of 1353016-70-2.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider