Yoshikawa, Chiaki published the artcileWell-defined monolith morphology regulates cell adhesion and its functions, HPLC of Formula: 1761-71-3, the publication is Materials Science & Engineering, C: Materials for Biological Applications (2019), 110108, database is CAplus and MEDLINE.
Hydrophilic epoxy resin-based monoliths were employed as cell culture substrates. The monoliths were made of a porous material with a bicontinuous structure that consisted of a porous channel and a resin skeleton. Monolith disks were prepared with a skinless surface through polymerization-induced spinodal decomposition-type phase separation The pore sizes, which were well controlled by the polymerization temperature, ranged from 70 to 380 nm. The quantity of protein adsorbed per unit area and the early-stage adhesion of HepG2 cells on the monolith substrates were independent of pore size, meaning they were not affected by surface topol. Long-term cell adhesion, as indicated by adherent cell number and shape, as well as liver-specific gene expression were significantly affected by pore size. In terms of cell shape, number, and gene expression, pores of approx. 200 nm were most suitable for HepG2 cell growth. These results highlight the importance of monolith morphol. for use as a cell culture substrate. The well-controlled morphol. demonstrated in this work indicates monoliths are capable of supporting growth for various types of cells in a range of applications.
Materials Science & Engineering, C: Materials for Biological Applications published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C6H6N2O, HPLC of Formula: 1761-71-3.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider