Synthesis and neuromuscular blocking activity of symmetrical bis- and poly-quaternary derivatives of quinuclidine and tropine was written by Chen, Shengquan;Yu, Shongtao;Geng, Rongliang;Dan, Zhiyi. And the article was included in Yaoxue Xuebao in 1987.Computed Properties of C7H16Cl2N2 This article mentions the following:
Title compounds e.g., I and II [Z = O, NOH; Z1 = (CH2)6, CH2OCH2; X = Br, Cl] were prepared from quinuclidine or tropine derivatives and their neuromuscular blocking activity was reported. In the experiment, the researchers used many compounds, for example, 3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2Computed Properties of C7H16Cl2N2).
3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2) belongs to quinuclidine derivatives.The reactions of quinuclidine compounds that lead to opening of the 1-azabi-cyclic system at the N-C and C-C bonds to give piperidine derivatives or, via subsequent rearrangements, derivatives of other heterocyclic systems, are correlated. Processes involving the fragmentation of quinuclidines in chemical reactions and under electron impact and reactions involving expansion of the quinuclidine ring and intermediate cleavage of the bicyclic system are examined.聽 Carbamoyl boranes are generally prepared as adducts with tertiary amines, such as trialkyl amines, pyridine, or quinuclidine, via two synthetic approaches based either on amidation of amine-carboxyborane adducts or on hydrolysis of amine-cyanoboranes.Computed Properties of C7H16Cl2N2
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider