Chhanda, Sadia Afrin et al. published their research in Journal of Catalysis in 2019 | CAS: 1204591-50-3

3,4-Bis(((1S)-quinolin-4-yl((2S)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione (cas: 1204591-50-3) belongs to quinuclidine derivatives.The reactions of quinuclidine compounds that lead to opening of the 1-azabi-cyclic system at the N-C and C-C bonds to give piperidine derivatives or, via subsequent rearrangements, derivatives of other heterocyclic systems, are correlated. Processes involving the fragmentation of quinuclidines in chemical reactions and under electron impact and reactions involving expansion of the quinuclidine ring and intermediate cleavage of the bicyclic system are examined.聽 Asymmetric construction of quinuclidine derivatives has been realized by an iridium-catalyzed allylic dearomatization reaction. The catalytic system, derived from [Ir(cod)Cl]2 and the Feringa ligand, tolerates a broad range of substrates. A large array of quinuclidine derivatives can be obtained under mild conditions in good to excellent yields (68%鈥?6%), diastereoselectivity (up to >20/1 dr), and enantioselectivity (up to >99% ee).Electric Literature of C42H44N6O2

Design and synthesis of chiral hyperbranched polymers containing cinchona squaramide moieties and their catalytic activity in the asymmetric Michael addition reaction was written by Chhanda, Sadia Afrin;Itsuno, Shinichi. And the article was included in Journal of Catalysis in 2019.Electric Literature of C42H44N6O2 This article mentions the following:

Chiral hyperbranched polymers (HBP) containing cinchona alkaloids were synthesized using a Mizoroki-Heck (MH) coupling polymerization reaction between a cinchona squaramide dimer and tri- or tetra-substituted aromatic iodides. This was a new type of polymeric chiral organocatalyst. We found that the as-obtained chiral HBPs show excellent catalytic activity in the asym. Michael reaction. Almost perfect enantioselectivity (>99% ee) was achieved in the reaction of 尾-ketoester and trans-尾-nitrostyrene. The three-dimensional network structure of the chiral HBPs is structurally robust and can be reused for further reaction without any loss in their catalytic activity. In the experiment, the researchers used many compounds, for example, 3,4-Bis(((1S)-quinolin-4-yl((2S)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione (cas: 1204591-50-3Electric Literature of C42H44N6O2).

3,4-Bis(((1S)-quinolin-4-yl((2S)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione (cas: 1204591-50-3) belongs to quinuclidine derivatives.The reactions of quinuclidine compounds that lead to opening of the 1-azabi-cyclic system at the N-C and C-C bonds to give piperidine derivatives or, via subsequent rearrangements, derivatives of other heterocyclic systems, are correlated. Processes involving the fragmentation of quinuclidines in chemical reactions and under electron impact and reactions involving expansion of the quinuclidine ring and intermediate cleavage of the bicyclic system are examined.聽 Asymmetric construction of quinuclidine derivatives has been realized by an iridium-catalyzed allylic dearomatization reaction. The catalytic system, derived from [Ir(cod)Cl]2 and the Feringa ligand, tolerates a broad range of substrates. A large array of quinuclidine derivatives can be obtained under mild conditions in good to excellent yields (68%鈥?6%), diastereoselectivity (up to >20/1 dr), and enantioselectivity (up to >99% ee).Electric Literature of C42H44N6O2

Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider