Stereoselective synthesis of epoxyisoprostanes: an organocatalytic and “pot-economy” approach was written by Weng, Jiang;Wang, Sheng;Huang, Lin-Jie;Luo, Zhang-Yi;Lu, Gui. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Electric Literature of C26H29ClN2O This article mentions the following:
An efficient and direct synthetic route to epoxyisoprostane EC Me ester (I) has been accomplished in 8 steps (10% overall yield) from readily available starting materials using a series of asym. organocatalytic reactions and one-pot operations. In the experiment, the researchers used many compounds, for example, (1S,2R,4S,5R)-1-Benzyl-2-(hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium chloride (cas: 69221-14-3Electric Literature of C26H29ClN2O).
(1S,2R,4S,5R)-1-Benzyl-2-(hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium chloride (cas: 69221-14-3) belongs to quinuclidine derivatives. Quinuclidine derivatives are also widely utilized as homogeneous or heterogeneous catalysts in various asymmetric processes such as Morita鈥揃aylis鈥揌illman reactions, Sharpless dihydroxylation reactions, and phase-transfer catalytic reactions. As a ligand, quinuclidine is useful in the studies of OsO4-catalyzed dihydroxylation of olefins. It plays an important role in the formation of onium salts used testing of PAC-antagonist activity.Electric Literature of C26H29ClN2O
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider