Synthesis of 6-fluoro-L-Dopa was written by Zhang, Lan;Tang, Ganghua;Yin, Duanzhi;Tang, Xiaolan;Wang, Yongxian. And the article was included in Zhongguo Yaowu Huaxue Zazhi in 2001.Computed Properties of C37H37BrN2O This article mentions the following:
Title compound, an important positron-emission tomog. (PET) tracer, was synthesized from 4-amino-1,2-dimethoxybenzene via phase transfer catalysis nucleophilic substitution, in nine steps, giving the product with satisfied yield. . In the experiment, the researchers used many compounds, for example, (1S,2S,4S,5R)-2-((R)-(Allyloxy)(quinolin-4-yl)methyl)-1-(anthracen-9-ylmethyl)-5-vinylquinuclidin-1-ium bromide (cas: 200132-54-3Computed Properties of C37H37BrN2O).
(1S,2S,4S,5R)-2-((R)-(Allyloxy)(quinolin-4-yl)methyl)-1-(anthracen-9-ylmethyl)-5-vinylquinuclidin-1-ium bromide (cas: 200132-54-3) belongs to quinuclidine derivatives. The development of synthetic approaches for efficient construction of novel quinuclidine derivatives is of great significance. Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 19.5. It can be prepared by reduction of quinuclidone.Computed Properties of C37H37BrN2O
Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider