Electric Literature of 871-91-0, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 871-91-0, Name is 7-Octyn-1-ol, SMILES is OCCCCCCC#C, belongs to quinuclidines compound. In a article, author is Gu, Jianhui, introduce new discover of the category.
Convenient new synthesis of umeclidinium bromide
Umeclidinium bromide, a drug used for chronic obstructive pulmonary disease, is synthesized through a new intermediate of phenyl(quinuclidin-4-yl)methanone. This novel method with simple operation flow and cheap reagents, makes it suitable for scale up. The overall four-step process provides umeclidinium bromide in 29% yield and the purity up to 99.83%. The X-ray crystal structure of the drug molecule was first reported.
Electric Literature of 871-91-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 871-91-0.
Reference:
Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider