Reference of 111-12-6, Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter. 111-12-6, Name is Methyl oct-2-ynoate, SMILES is CCCCCC#CC(OC)=O, belongs to quinuclidines compound. In a article, author is Nagashima, Shinya, introduce new discover of the category.
Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists
Herein, we describe the synthesis and pharmacological profiles of novel quinuclidinyl heteroarylcarbamate derivatives. Among them, the quinuclidin-4-yl thiazolylcarbamate derivative ASP9133 was identified as a promising long-acting muscarinic antagonist (LAMA) showing more selective inhibition of bronchoconstriction against salivation and more rapid onset of action in a rat model than tiotropium bromide. (C) 2014 Elsevier Ltd. All rights reserved.
Reference of 111-12-6, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 111-12-6.
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Quinuclidine – Wikipedia,
,Quinuclidine | C7H13N | ChemSpider