Sutton, James C. published the artcileSolid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors, Application of 4-Cyclohexylbenzoic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2004), 14(9), 2233-2239, database is CAplus and MEDLINE.
A series of non-guanidine N1-activated C4-carboxy azetidinone tryptase inhibitors, e.g. I, was prepared by solid-phase methodol. to quickly assess the SAR associated with distal functionality on the N1-activating group. From these studies, potent inhibitors with improved specificity were discovered.
Bioorganic & Medicinal Chemistry Letters published new progress about 20029-52-1. 20029-52-1 belongs to quinuclidine, auxiliary class Carboxylic acid,Benzene, name is 4-Cyclohexylbenzoic acid, and the molecular formula is C5H9IO2, Application of 4-Cyclohexylbenzoic acid.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider