Habicht, J. published the artcileInhibition of prostaglandin E2 release by salicylates, benzoates and phenols: a quantitative structure-activity study, SDS of cas: 20029-52-1, the publication is Journal of Pharmacy and Pharmacology (1983), 35(11), 718-23, database is CAplus and MEDLINE.
Concentrations inhibiting 50% of PGE2 [363-24-6] release from phorbol ester-stimulated mouse peritoneal macrophages in vitro were determined for monosubstituted congeners of salicylic acid, benzoic acid, and phenol. Other compounds, mainly benzoic acids, were inactive. An attempt was made to establish QSAR from the exptl. data using literature or calculated values for the logarithmic octanol-water partition coefficients of the compounds, molar refractivity and sigma values of substituents as well as structural indicator variables. The equations had moderate predictive power and should be considered as a 1st step in the investigation of factors determining the biog. activity of salicylates, benzoates, and phenols.
Journal of Pharmacy and Pharmacology published new progress about 20029-52-1. 20029-52-1 belongs to quinuclidine, auxiliary class Carboxylic acid,Benzene, name is 4-Cyclohexylbenzoic acid, and the molecular formula is C13H16O2, SDS of cas: 20029-52-1.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider