Category: 1761-71-3

Chaudhari, Chandan published the artcileOne-pot synthesis of cyclohexylamine and N-aryl pyrroles via hydrogenation of nitroarenes over the Pd_0.5Ru_0.5-PVP catalyst, Category: quinuclidine, the publication is New Journal of Chemistry (2021), 45(22), 9743-9746, database is CAplus.

The direct synthesis of cyclohexylamine via the hydrogenation of nitrobenzene over monometallic (Pd, Ru or Rh) and bimetallic (Pd_xRu_1-x) catalysts was studied. The Pd_0.5Ru_0.5-PVP catalyst was the most effective catalyst for this reaction. The catalyst can be reused and applied for the synthesis of N-aryl pyrroles I (R = Ph, 4-chlorophenyl, pyridin-3-yl, etc.) and quinoxalines such as 2,3-diphenylquinoxaline and 2,3-diphenyl-1,2,3,4-tetrahydroquinoxaline from nitrobenzenes RNO₂.

New Journal of Chemistry published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Category: quinuclidine.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Lambeth, Robert H. published the artcileMechanical and adhesive properties of hybrid epoxy-polyhydroxyurethane network polymers, Product Details of C13H26N2, the publication is Polymer (2019), 121881, database is CAplus.

Epoxy resins and polyurethanes are both important classes of materials with wide-ranging applications. The merging of both chemistries presents new opportunities to investigate materials with potentially unique or improved performance. In this work, a series of formulations with varying levels of epoxy and cyclic carbonate monomers were reacted with a multifunctional amine to produce network polymers with hybrid functionality. The spectroscopic, swelling, thermal-mech., tensile, and adhesive behaviors were evaluated. The materials performed as expected based on the proposed network structure as determined through small-mol. model studies. In particular, the hybrid network polymers performed admirably as adhesives with significantly improved performance over an epoxy-amine control.

Polymer published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Product Details of C13H26N2.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Shoji, Naoyuki published the artcileEffect of conversion on epoxy resin properties: Combined molecular dynamics simulation and experimental study, Related Products of quinuclidine, the publication is Polymer (2022), 125041, database is CAplus.

We investigated epoxy resin consisting of diglycidyl ether of bisphenol A (DGEBA) and bis-(p-aminocyclohexyl)methane (PACM) and found that the d. increased and decreased in the low- and high-conversion regions, resp., by using experiments and all-atom (AA) mol. dynamics (MD) simulations. To understand this feature qual., we conducted course-grained (CG) MD simulations. For the flexible and rigid CG models, the calculated d. increased and decreased monotonically, resp., in contrast to the exptl. d. To develop a more realistic CG model, which is denoted as CG-EP, we derived angular parameters based on AA-MD simulations. It was found that the CG-EP successfully reproduced the trend of the exptl. d., suggesting the importance of mol. flexibility. In addition, the progress of the conversion monotonically increased the free volume hole size, which is consistent with the result of positron annihilation lifetime spectroscopy. Furthermore, we exptl. observed that the Young’s modulus suddenly decreased at 50%, as the conversion progressed. The CG anal. indicated that this trend was also attributed to the mol. flexibility.

Polymer published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C39H35N5O8, Related Products of quinuclidine.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Yoshikawa, Chiaki published the artcileWell-defined monolith morphology regulates cell adhesion and its functions, HPLC of Formula: 1761-71-3, the publication is Materials Science & Engineering, C: Materials for Biological Applications (2019), 110108, database is CAplus and MEDLINE.

Hydrophilic epoxy resin-based monoliths were employed as cell culture substrates. The monoliths were made of a porous material with a bicontinuous structure that consisted of a porous channel and a resin skeleton. Monolith disks were prepared with a skinless surface through polymerization-induced spinodal decomposition-type phase separation The pore sizes, which were well controlled by the polymerization temperature, ranged from 70 to 380 nm. The quantity of protein adsorbed per unit area and the early-stage adhesion of HepG2 cells on the monolith substrates were independent of pore size, meaning they were not affected by surface topol. Long-term cell adhesion, as indicated by adherent cell number and shape, as well as liver-specific gene expression were significantly affected by pore size. In terms of cell shape, number, and gene expression, pores of approx. 200 nm were most suitable for HepG2 cell growth. These results highlight the importance of monolith morphol. for use as a cell culture substrate. The well-controlled morphol. demonstrated in this work indicates monoliths are capable of supporting growth for various types of cells in a range of applications.

Materials Science & Engineering, C: Materials for Biological Applications published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C6H6N2O, HPLC of Formula: 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Francisco, Vitor published the artcileA high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies, Product Details of C13H26N2, the publication is Methods (Amsterdam, Netherlands) (2021), 13-25, database is CAplus and MEDLINE.

RNA-based therapies are highly selective and powerful regulators of biol. functions. Non-viral vectors such as nanoparticles (NPs) are very promising formulations for the delivery of RNA-based therapies but their cell targeting, cell internalization and endolysomal escape capacity is rather limited. Here, we present a methodol. that combines high-throughput synthesis of light-triggerable NPs and a high-content imaging screening to identify NPs capable of efficiently delivering different type of RNAs. The NPs were generated using polymers synthesized by Michael type addition reactions and they were designed to: (i) efficiently complex coding (mRNAs) and non-coding (miRNAs and/or lncRNAs) RNA mols., (ii) allow rapid cell uptake and cytoplasmic release of RNA mols. and (iii) target different cell types based on their composition Furthermore, light-responsive domains were attached to the polymers by distinctive methods to provide diverse disassembly strategies. The most efficient formulations were identified using cell-based assays and high-content imaging anal. This strategy allows precise delivery of RNA-based therapies and provides an effective design approach to address critical issues in non-viral gene delivery.

Methods (Amsterdam, Netherlands) published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Product Details of C13H26N2.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Wolosz, Dominik published the artcileEnvironmentally Friendly Synthesis of Urea-Free Poly(carbonate-urethane) Elastomers, Name: 4,4-Diaminodicyclohexyl methane, the publication is Macromolecules (Washington, DC, United States) (2022), 55(12), 4995-5008, database is CAplus.

This work presents an eco-friendly synthetic pathway toward non-isocyanate poly(carbonate-urethane)s (NIPCUs) obtained from carbon dioxide and its simple derivatives-organic carbonates. Bis(hydroxyalkyl carbamate)s synthesized from ethylene carbonate and appropriate α,ω-diamines were used as polyurethane hard segment precursors while oligocarbonate diols as soft segment ones. The structures and properties of the obtained NIPCUs were explored by means of ¹H NMR, ¹³C NMR, and FT-IR spectroscopies, MALDI-ToF mass spectrometry, DSC, and mech. testing. Based on spectroscopic data as well as model reactions, it was demonstrated that the formation of the urea bonds was suppressed due to the presence of carbonate moieties. The reaction of urea bonds with carbonate residues led to urethane group formation. In addition, the influence of the polyurethane structure on the mech. and thermal properties of the obtained polymers was studied. The obtained NIPCUs exhibited mech. properties comparable to conventional polyurethane elastomers (e.g., a tensile strength of 32 MPa and an elongation at break of 800%). The described synthetic route is an straightforward way toward the replacement of conventional polyurethanes with environmentally friendly ones.

Macromolecules (Washington, DC, United States) published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C9H8O4, Name: 4,4-Diaminodicyclohexyl methane.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Nara, Mayuko published the artcileWhite-Light Emission and Tunable Luminescence Colors of Polyimide Copolymers Based on FRET and Room-Temperature Phosphorescence, Quality Control of 1761-71-3, the publication is ACS Omega (2020), 5(24), 14831-14841, database is CAplus and MEDLINE.

Thermally stable copolyimide (CoPI) films exhibiting high optical transparency and room-temperature phosphorescence (RTP) were prepared by copolymerizing fluorescent dianhydride and brominated phosphorescent dianhydride with an alicyclic diamine. The CoPI films underwent a 5 wt % degradation at a temperature higher than 349°C and exhibited dual fluorescent and phosphorescent emissions owing to their efficient Forster resonance energy transfer from the fluorescent to phosphorescent dianhydride moieties in the main chains, followed by an intersystem crossing from the singlet to triplet state of the latter moiety atoms. The CoPIs displayed bright RTP under a vacuum with various colors produced when adjusting the copolymerization ratio. CoPI with 5 mol % phosphorescent moiety (CoPI-05) emitted white light with high optical transparency owing to the suppression of the PI chain aggregation that causes a yellowish coloration. The copolymerization of fluorescent and phosphorescent PI moieties can control the photoluminescent properties of PI films and is applicable to color-tunable solid-state emitters, ratiometric oxygen sensors, and solar-spectrum converters.

ACS Omega published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Quality Control of 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Fujiwara, Eisuke published the artcileUltrafast Spectroscopic Analysis of Pressure-Induced Variations of Excited-State Energy and Intramolecular Proton Transfer in Semi-Aliphatic Polyimide Films, Safety of 4,4-Diaminodicyclohexyl methane, the publication is Journal of Physical Chemistry B (2021), 125(9), 2425-2434, database is CAplus and MEDLINE.

The relationship between the photoexcitation dynamics and the structures of semi-aliphatic polyimides (3H-PIs) was investigated using ultrafast fluorescent emission spectroscopy at atm. and increased pressures of up to 4 GPa. The 3H-PI films exhibited prominent fluorescence with extremely large Stokes shifts (Δν > 10 000 cm^-1) through an excited-state intramol. proton transfer (ESIPT) induced by keto-enol tautomerism at the isolated dianhydride moiety. The incorporation of bulky -CH₃ and -CF₃ side groups at the diamine moiety of the PIs increased the quantum yields of the ESIPT fluorescence owing to an enhanced interchain free volume In addition, 3H-PI films emitted another fluorescence at shorter wavelengths originating from closely packed polyimide (PI) chains (in aggregated forms), which was mediated through a Foddorster resonance energy transfer (FRET) from an isolated enol form into aggregated forms. The FRET process became more dominant than the ESIPT process at higher pressures owing to an enhancement of the FRET efficiency caused by the increased dipole-dipole interactions associated with a densification of the PI chain packing. The efficiency of the FRET rapidly increased by applying pressure up to 1 GPa owing to an effective compression of the interchain free volume and addnl. gradually increased at higher pressures owing to structural and/or conformational changes in the main chains.

Journal of Physical Chemistry B published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Safety of 4,4-Diaminodicyclohexyl methane.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Hui, Xiang published the artcileHighly efficient synthesis of novel bio-based pentamethylene dicarbamate via carbonylation of pentanediamine with ethyl carbamate over well-defined titanium oxide catalysts, Category: quinuclidine, the publication is Catalysis Science & Technology (2022), 12(7), 2315-2327, database is CAplus.

Carbonylation of pentanediamine (PDA) is a green and effective route for the synthesis of pentamethylene dicarbamate (PDC), an important intermediate compound for the preparation of polyurethanes (PUs) and other chems. In this work, TiO₂-101 and TiO₂-110 catalysts, with preferential exposure of (101) and (110) facets, resp., were prepared and studied for the carbonylation of diamines with Et carbamate (EC) to give dicarbamates, e.g., EtO₂C(CH₂)₇NHCO₂Et and I. The catalysts were characterized by various techniques, including XRD, BET, SEM, TEM, XPS, NH₃-TPD and in situ FTIR. The characterization results indicated that TiO₂ catalysts with exposed (110) and (101) facets were synthesized successfully. The overall results suggested that the (101) facets on the TiO₂ surface provide high amounts of surface Lewis acid sites that played a pivotal role in PDC formation, which gave a conversion and yield both up to 99% under optimized conditions. In situ FTIR spectroscopy clearly revealed that polyurea as an intermediate was formed in the reaction and subsequently converted to PDC catalyzed by the TiO₂ catalyst. Furthermore, the DFT results showed that the conversion of polyurea to PDC over the (101) facets was more prone to occur than the (110) facets due to the lower reaction energy barrier. In addition, the TiO₂-101 catalyst displayed excellent stability without an obvious activity decline after five cycles.

Catalysis Science & Technology published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Category: quinuclidine.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Kumar, Amit published the artcileHydrogenative Depolymerization of Nylons, Synthetic Route of 1761-71-3, the publication is Journal of the American Chemical Society (2020), 142(33), 14267-14275, database is CAplus and MEDLINE.

The widespread crisis of plastic pollution demands discovery of new and sustainable approaches to degrade robust plastics such as nylons. Using a green and sustainable approach based on hydrogenation, in the presence of a ruthenium pincer catalyst at 150 oC and 70 bar H2, we report here the first example of hydrogenative depolymerization of conventional, widely used nylons, and polyamides in general. Under the same catalytic conditions, we also demonstrate the hydrogenation of a polyurethane to produce diol, diamine and methanol. Addnl., we demonstrate an example where monomers (and oligomers) obtained from the hydrogenation process can be dehydrogenated back to a poly(oligo)amide of approx. similar mol. weight, thus completing a closed loop cycle for recycling of poly-amides. Based on the exptl. and DFT studies, we propose a catalytic cycle for the process that is facilitated by metal-ligand cooperativity. Overall, this unprecedented transformation, albeit at the proof of concept level, offers a new approach towards a cleaner route to recycling nylons.

Journal of the American Chemical Society published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Synthetic Route of 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider