Category: 1761-71-3

Sugimoto, Yuka published the artcileEvaluation of heat resistance of metal-resin bonding using epoxy monoliths prepared with various epoxy resins and diamine curing agents, Safety of 4,4-Diaminodicyclohexyl methane, the publication is Nippon Setchaku Gakkaishi (2020), 56(8), 303-313, database is CAplus.

Epoxy monoliths with a co-continuous porous structure were produced by a thermosetting reaction using combinations oi 4 kinds of epoxy resins, 9 kinds of diamine curing agents, and 2 kinds porogens (pore forming agents), and applied to dissimilar materials bonding between metals and engineering plastics. An epoxy monolith was prepared on a stainless or copper plate, and a polycarbonate or poly (phenylene sulfide) plate was thermally welded to prepare a bonding test piece. The heat resistance of the epoxy monolith bonding systems used in this study was evaluated from the results of the tensile shear test before and after heat treatment. In addition, the thermogravimetric anal. of the monolith materials revealed the thermal decomposition behavior of the cured epoxy. Based on these results, the effects of the structure and the number of functional groups of the epoxy resins and the diamine curing agents on the porous structure bonding strength, and heat resistance of the epoxy monoliths were discussed.

Nippon Setchaku Gakkaishi published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C14H17FN4O3, Safety of 4,4-Diaminodicyclohexyl methane.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Sakata, Nanako published the artcileInterfacial Structure Control and Three-Dimensional X-ray Imaging of an Epoxy Monolith Bonding System with Surface Modification, HPLC of Formula: 1761-71-3, the publication is Langmuir (2020), 36(37), 10923-10932, database is CAplus and MEDLINE.

A monolith bonding system has a high reliability for dissimilar material bonding. The epoxy monolith layer fabricated on a substrate guarantees bond strength by the anchor effect, regardless of the compatibility of the used materials. Designing a high-performance monolith bonding system requires the suppression of an interfacial failure between the monolith and the substrate. In this study, silane and phosphine coupling agents containing amino and epoxy groups were used to construct a robust interfacial structure between the monolith and the substrates such as glass and metals. The internal and interfacial monolith structures were characterized by three-dimensional X-ray imaging as a nondestructive observation method in addition to the SEM of the sample cross sections. The modification of the substrate-monolith interface using the coupling agents improved the strength of dissimilar material bonding of the glass and metal substrates in combination with thermoplastic resins such as poly(ethylene terephthalate) and polycarbonate bisphenol-A.

Langmuir published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, HPLC of Formula: 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Khodaverdian, Verjine published the artcileDeferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study, Synthetic Route of 1761-71-3, the publication is Scientific Reports (2019), 9(1), 1-17, database is CAplus and MEDLINE.

Deferiprone (DFP) is a hydroxypyridinone-derived iron chelator currently in clin. use for iron chelation therapy. DFP has also been known to elicit antiproliferative activities, yet the mechanism of this effect has remained elusive. We herein report that DFP chelates the Fe²⁺ ion at the active sites of selected iron-dependent histone lysine demethylases (KDMs), resulting in pan inhibition of a subfamily of KDMs. Specifically, DFP inhibits the demethylase activities of six KDMs – 2A, 2B, 5C, 6A, 7A and 7B – with low micromolar IC₅₀s while considerably less active or inactive against eleven KDMs – 1A, 3A, 3B, 4A-E, 5A, 5B and 6B. The KDM that is most sensitive to DFP, KDM6A, has an IC₅₀ that is between 7- and 70-fold lower than the iron binding equivalence concentrations at which DFP inhibits ribonucleotide reductase (RNR) activities and/or reduces the labile intracellular zinc ion pool. In breast cancer cell lines, DFP potently inhibits the demethylation of H3K4me3 and H3K27me3, two chromatin posttranslational marks that are subject to removal by several KDM subfamilies which are inhibited by DFP in cell-free assay. These data strongly suggest that DFP derives its anti-proliferative activity largely from the inhibition of a sub-set of KDMs. The docked poses adopted by DFP at the KDM active sites enabled identification of new DFP-based KDM inhibitors which are more cytotoxic to cancer cell lines. We also found that a cohort of these agents inhibited HP1-mediated gene silencing and one lead compound potently inhibited breast tumor growth in murine xenograft models. Overall, this study identified a new chem. scaffold capable of inhibiting KDM enzymes, globally changing histone modification profiles, and with specific anti-tumor activities.

Scientific Reports published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Synthetic Route of 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Kalita, Deep J. published the artcileNovel bio-based epoxy resins from eugenol as an alternative to BPA epoxy and high throughput screening of the cured coatings, Application In Synthesis of 1761-71-3, the publication is Polymer (2021), 124191, database is CAplus.

A novel vinyl ether monomer from eugenol, 2-eugenoloxyvinyl ether (EEVE), was synthesized and used as a building block for polymeric epoxy resins. The EEVE monomer was polymerized via cationic polymerization of the vinyl ether group leaving the allylic functionality of eugenol available for further epoxidation Epoxidized poly(EEVE) resins varying in levels of epoxidation (epoxy equivalent weights from 360 to 870 g/equiv) were produced and cured with twelve amine curatives at ambient and elevated temperatures for different time intervals to evaluate and optimize the curing regime. The cured coatings were screened with high throughput dye extraction and “conventional” coating testing methods and compared to coatings produced from diglycidyl ether of bisphenol-A (DGEBA). Results showed that coatings derived from epoxidized poly(EEVE) [Epoly(EEVE)] can be tuned from soft and elastic with hardness <50 GPa and glass transition temperatures (T_gs) <20° to hard and brittle with hardness >500 GPa and T_gs>60° by varying the extent of epoxidation and the nature of curative, whereas DGEBA resulted in hard and brittle coatings irresp. of the type of curative used in the study. Compared to DGEBA resin, coatings with similar or higher crosslink densities and hardness were obtained from Epoly(EEVE) resins with >50% epoxidation of EEVE moieties using the same curative and curing regime. These partially biobased epoxy compounds derived from eugenol have the potential to be competitive with petroleum-based DGEBA resins in coatings applications.

Polymer published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Application In Synthesis of 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Tanaka, Takaaki published the artcileElectrical properties of crosslinked aliphatic polyurea thin films prepared by vapor deposition polymerization, Synthetic Route of 1761-71-3, the publication is Japanese Journal of Applied Physics (2020), 59(3), 036502, database is CAplus.

Vapor deposition polymerization (VDP) is a method for producing high-performance polymeric thin films, such as polyimide, polyamide and polyurea, by co-evaporation of two types of bi-functional monomers on the substrate surface. Polymeric films obtained by VDP have a high dielec. constant and high breakdown voltage and low impurity content due to being solvent-free. In this study, polyurea thin films were prepared by VDP. The relation between the elec. properties and the chem. structures was investigated by IR spectroscopy. The IR spectra of the crosslinked aliphatic polyurea thin films indicated strong intermol. hydrogen bonds even in the disordered network structure without mol. orientation. In addition, the crosslinking agent gave rise to an increase in the concentration of urea groups. Both effects of the crosslinking agent may have contributed to the simultaneous improvement of the dielec. constant and the dielec. loss, even though they generally have a trade-off relationship.

Japanese Journal of Applied Physics published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C8H5IO, Synthetic Route of 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Hubbard, Robert L. published the artcileAn empirically derived model for further increasing microwave curing rates of epoxy-amine polymerizations, Product Details of C13H26N2, the publication is Journal of Applied Polymer Science (2021), 138(1), 49635, database is CAplus.

The reaction rates of common epoxy resins with diamine crosslinking agents in uniform microwave fields have been compared according to a variety of structural features. A statistically designed exptl. matrix was used to determine that the curing rates were linearly dependent on only two significant variables, amine basicity, and degrees of rotational freedom (entropy) of the reactants. Surprisingly, the mol. polarizability, which is commonly understood to be responsible for the transfer of microwave electromagnetic energy to mols. with permanent dipoles, had no significant effect even as a dependent variable. A very high probability model was produced that accurately predicts the reactivities of epoxide and diamine reactants with respect to specific structural features. Further evidence is provided for a dominant linear pregelation polymerization and a uniform microwave reaction field.

Journal of Applied Polymer Science published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Product Details of C13H26N2.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Meyer, Christopher S. published the artcileMesoscale modeling of ballistic impact experiments on a single layer of plain weave composite, Name: 4,4-Diaminodicyclohexyl methane, the publication is Composites, Part B: Engineering (2022), 109753, database is CAplus.

To gain fundamental understanding of energy absorbing mechanisms during high velocity impact of plain weave S-2 glass/epoxy composites, single layer composites are ballistically tested and modeled. To avoid boundary condition effects, targets were 0.6 m by 0.6 m with free boundaries. Targets were perforated by 17 grain, 0.22 caliber fragment simulating projectiles. Experiments focused on determining ballistic limit velocity and the associated damage modes. The experiments were simulated with a continuum finite element model with effective plain weave properties that predicted the ballistic limit velocity with 6% error. A mesoscale model that incorporates the woven fabric architecture and lower length scale energy absorbing mechanisms was also developed. The mesoscale model includes accurate geometry and fiber volume fraction, rate-dependent matrix behavior, and important damage mechanisms including tow-tow delamination, tow pullout and frictional sliding. The mesoscale model predicted ballistic limit velocity with 1% error and more accurately predicts the deformation modes during ballistic impact and penetration than the continuum modeling approach. The mesoscale model indicated two phases of penetration, the first dominated by momentum transfer and the second dominated by tow tension and pullout. In a materials-by-design framework, the mesoscale model was used to quantify energy dissipation and identify important damage mechanisms that could be optimized to provide improved ballistic penetration resistance.

Composites, Part B: Engineering published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Name: 4,4-Diaminodicyclohexyl methane.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Masutani, Yusuke published the artcileShape memory property of carbon fiber / epoxy resin composite materials, HPLC of Formula: 1761-71-3, the publication is Zairyo (2021), 70(1), 25-30, database is CAplus.

The authors investigated an effect of carbon fiber on shape memory property of carbon fiber / shape memory polymer (epoxy resin) composites by using dynamic mech. anal. (DMA), shape memory test, and mech. constitutive model. As a result of DMA, the storage modulus (E’) of the composite material (CF/EP) was improved by CF component, as compared with that of the pure epoxy resin (pure EP). Especially, E’ at rubbery region was remarkably increased with two decades. From the results of shape memory test, CF/EP showed good shape recovery behavior as well as pure EP. Contrary, the shape fixity ratio of CF/EP was lower than that of pure EP. This is because that the difference in E’ below / above the glass transition temperature (T_g) of CF/EP became smaller (less than one decade) than pure EP (two decades). In addition, the shape recovery of CF/EP started at lower temperature than T_g, although the recovery of pure EP showed around T_g. In order to examine the shape recovery behavior of CF/EP, the authors compared the viscoelastic properties of three samples, pure EP, CF layer and the composite. As a result, the CF layer had higher E’ than CF/EP, and no significant change in E’ occurred around T_g. From the results, the authors speculated that the CF layer acted as a shape recovery component for the composite material. Furthermore, the authors proposed a mech. constitutive model, in which the CF layer was assumed as the recover component, to qual. explain the shape recovery behavior of CF/EP composite. The simulated result by the constitutive model reproduced the trend of anomalous shape recovery behavior below T_g of CF/EP.

Zairyo published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, HPLC of Formula: 1761-71-3.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Tominaga, Ren published the artcileCo-continuous network polymers using epoxy monolith for the design of tough materials, COA of Formula: C13H26N2, the publication is Scientific Reports (2021), 11(1), 1431, database is CAplus and MEDLINE.

High-performance polymer materials that can exhibit distinguished mech. properties have been developed based on material design considering energy dissipation by sacrificial bond dissociation We now propose co-continuous network polymers (CNPs) for the design of tough polymer materials. CNP is a new composite material fabricated by filling the three-dimensionally continuous pores of a hard epoxy monolith with any cross-linked polymer having a low glass transition temperature (Tg). The structure and mech. properties of the CNPs containing epoxy resins, thiol-ene thermosets, and polyacrylates as the low-Tg components were investigated by differential scanning calorimetry, dynamic mech. anal., tensile tests as well as scanning electron microscopic observations and non-destructive 3D X-ray imaging in order to clarify a mechanism for exhibiting an excellent strength and toughness. It has been demonstrated that the mech. properties and fractural behavior of the CNPs significantly depend on the network structure of the filler polymers, and that a simultaneous high strength and toughness are achieved via the sacrificial fracture mechanism of epoxy-based hard materials with co-continuous network structures.

Scientific Reports published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C8H16O2, COA of Formula: C13H26N2.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider

Romero-Zuniga, Gabriela Yolotzin published the artcileEnhanced mechanical performance of a DGEBA epoxy resin-based shape memory polymer by introducing graphene oxide via covalent linking, Recommanded Product: 4,4-Diaminodicyclohexyl methane, the publication is Journal of Applied Polymer Science (2022), 139(2), 51467, database is CAplus.

Shape memory polymers (SMP) are prepared, via dual thiol-epoxy/thiol-ene reactions, from diglycidyl ether of bisphenol A (DGEBA), a trithiol (TMP), a tetraallyl amine (TAA), and small amounts (0.1-0.5 weight%) of graphene oxide either pristine (GO) or functionalized with methacrylate groups (GO_M). The incorporation of GO_M to the epoxy resin network permits a good load transfer, which is reflected in improved properties such as Young modulus (from 220 to 519 MPa), tensile strength (from 46.3 to 69.2 MPa), Izod impact strength (from 0.051 to 0.42 J/mm), torque (from 0.008 to 0.031 Nm), and glass transition temperature (from 75 to 105°C). Such improvement in properties is attributed to the incorporation of GO_M via covalent linking, which is a good strategy for improving polymer-particle interaction and particle dispersion. The epoxy-based SMP also show high storage modulus (up to 2.36 GPa) and high deformation capacity, which are reflected in good shape fixity (between 97% and 100%) and thermo-induced shape recovery (between 97% to 99.7%) behaviors in flexion mode tests.

Journal of Applied Polymer Science published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Recommanded Product: 4,4-Diaminodicyclohexyl methane.

Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider