Category: 6530-09-2

Thiol-ene Click Reaction as a General Route to Functional Trialkoxysilanes for Surface Coating Applications was written by Tucker-Schwartz, Alexander K.;Farrell, Richard A.;Garrell, Robin L.. And the article was included in Journal of the American Chemical Society in 2011.Electric Literature of C7H16Cl2N2 This article mentions the following:

Functionalized trialkoxysilanes are widely used to modify the surface properties of materials and devices. It will be shown that the photoinitiated radical-based thiol-ene “click” reaction provides a simple and efficient route to diverse trialkoxysilanes. A total of 15 trialkoxysilanes were synthesized by reacting either alkenes with 3-mercaptopropyltrialkoxysilane or thiols with allyltrialkoxysilanes in the presence of a photoinitiator. The functionalized trialkoxysilanes were obtained in quant. to near-quant. yields with high purity. The photochem. reactions can be run neat in standard borosilicate glassware using a low power 15 W blacklight. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. To demonstrate that these silanes can be used as surface coating agents, several were reacted with iron oxide superparamagnetic nanoparticles and the loadings quantified. The photoinitiated thiol-ene reaction thus offers a facile and efficient method for preparing surface-active functional trialkoxysilanes. In the experiment, the researchers used many compounds, for example, 3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2Electric Literature of C7H16Cl2N2).

3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2) belongs to quinuclidine derivatives. Quinuclidine acts as a catalyst, a chemical building block and is used in organic synthesis. Traditionally, quinuclidine scaffolds can be constructed by second-order nucleophilic substitution (SN2) reaction or condensation reaction of piperidine derivatives. However, most of these reactions are racemic or chiral auxiliary-assisted processes.Electric Literature of C7H16Cl2N2

Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider

Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating ‘stitching’ annulation approach was written by Rice, Scott;Cox, Daniel J.;Marsden, Stephen P.;Nelson, Adam. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2021.Computed Properties of C7H16Cl2N2 This article mentions the following:

Regioselective and stereospecific directed C-H arylation of simple amine substrates e.g., exo-2-aminonorbornane, and cyclisation, delivered three-dimensional scaffolds e.g., (1R,3aR,4R,10bS)-2,3,3a,4,5,10b-hexahydro-1,4-methanobenzo[c]cyclopenta[e]azepin-6(1H)-one. The unified approach significantly expanded the range of bridged ring systems that contain both a nitrogen atom and an aromatic ring. In the experiment, the researchers used many compounds, for example, 3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2Computed Properties of C7H16Cl2N2).

3-Aminoquinuclidine dihydrochloride (cas: 6530-09-2) belongs to quinuclidine derivatives. Quinuclidine acts as a catalyst, a chemical building block and is used in organic synthesis. Asymmetric construction of quinuclidine derivatives has been realized by an iridium-catalyzed allylic dearomatization reaction. The catalytic system, derived from [Ir(cod)Cl]2 and the Feringa ligand, tolerates a broad range of substrates. A large array of quinuclidine derivatives can be obtained under mild conditions in good to excellent yields (68%–96%), diastereoselectivity (up to >20/1 dr), and enantioselectivity (up to >99% ee).Computed Properties of C7H16Cl2N2

Referemce:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider